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Product name:
Venlaxin SR
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Generic name:
ونلافکسین آهسته رهش
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Dosage form:
Oral capsules
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Packaging:
Venlaxin SR 75: Box of 4 blisters of 15 capsules. Venlaxin SR 150: Box of 5 blisters of 10 capsules.
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Drug Category:
Neurology and Psychiatry
Indications:
Major depressive episodes (MDD)
Panic disorder with or without agoraphobia (PD)
Social anxiety disorder (social phobia/SAD)
Generalised anxiety disorder (GAD)
Dosage and Administration:
Take once daily with food . Capsules should be taken whole; do not divide, crush, chew, or dissolve .
When discontinuing treatment, reduce the dose gradually .
Renal impairment: reduce the total daily dose by 25% to 50% in patients with renal impairment. Reduce the total daily dose by 50% or more in patients undergoing dialysis or with severe renal impairment .
Hepatic impairment: reduce the daily dose by 50% in patients with mild to moderate hepatic impairment. In patients with severe hepatic impairment or hepatic cirrhosis, it may be necessary to reduce the dose by more than 50%.
Contraindication:
Hypersensitivity to venlafaxine or to any of the excipients.
Concomitant treatment with irreversible monoamine oxidase inhibitors (MAOIs) is contraindicated due to the risk of serotonin syndrome with symptoms such as agitation, tremor and hyperthermia. Venlafaxine must not be initiated for at least 14 days after discontinuation of treatment with an irreversible MAOI. Venlafaxine must be discontinued for at least 7 days before starting treatment with an irreversible MAOI.
